Iverpraz is indicated for the treatment of parasitic infestations in horse.
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A white to off white homogenous oral paste.
Each gram of Ivermectin Praziquantel Paste for Horse contains:
Ivermectin 18.7 mg
Praziquantel 140.3 mg
For the treatment of mixed cestode and nematode or arthropod infestations, due to adult and immature roundworms, lungworms, bots and tapeworms in horses:
Large strongyle: Strongylus vulgaris (adult and arterial larvae), Strongylus edentatus (adult and L4 tissue larval stages), Strongylus equinus (adult), Tridontophorus spp. (adult)
Small strongyle: Cyathostomum: Cylicocyclus spp., Cylicostephanus spp.,
Cylicodontophorus spp., Gyalocephalus spp. (adult and non-inhibited mucosal
Parascaris: Parascaris equorum (adult and larvae)
Oxyuris: Oxyuris equi (larvae)
Trichostrongylus: Trichostrongylus axei (adult)
Strongyloides: Strongyloides westeri (adult)
Habronema: Habronema spp. (adult)
Onchocerca: Onchocerca spp. microfilariae i.e. cutaneous onchocerciasis
Lungworm: Dictyocaulus arnfieldi (adult and larvae)
Cestodes (Tapeworm): Anoplocephala perfoliata, Anoplocephala magna,
Paranoplocephala mamillana (adult)
Dipteran insects: Gasterophilus spp. (larvae)
As tapeworm infestation is unlikely to occur in horses before two months of age, treatment of foals below this age is not considered necessary.
Dosage & Administration
200 µg of Ivermectin and 1.5 mg of Praziquantel per kg of bodyweight corresponding to 1.07 g of paste per 100 kg bodyweight
To ensure administration of a correct dose, bodyweight should be determined as accurately as possible; accuracy of the dosing device should be checked as underdosing might lead to an increased risk of development of resistance to anthelmintic drugs.
The first division delivers enough paste to treat 50 kgs.
Each subsequent syringe division delivers enough paste to treat 50 kgs of bodyweight. The syringe should be adjusted to the calculated dosage by setting the ring on the appropriate place on the plunger. The syringe containing 7.49 g of paste delivers sufficient paste to treat 700 kg of bodyweight at the recommended dose rate.
Horses: Meat & Offal: 35 days
Not permitted for use in horses producing milk for human consumption.
Contraindictions, Warnings etc
Do not use in foals under 2 weeks of age.
Do not use in mares from which milk is taken for human consumption.
Do not use in horses known to be hypersensitive to active ingredients or to any other ingredients.
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
- Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device
Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
Resistance to ivermectin (an avermectin) has been reported in Parascaris equorum in horses in a number of countries including the EU. Therefore the use of this product should be based on local (regional farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
Do not store above 30°C
Store open syringes below 23°C
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE.
Do not contaminate surface waters or ditches with the product or used container. Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements